Bruise-eze

WHAT IS BRUISE-EZE®?

Simply put, it is a topical cream that helps speed up the natural healing process of bruises.

But bruising is not its only area of use!

It has a unique mode of action to other products on the market

It can provide an effective treatment option for certain medical conditions that otherwise have poor treatment outcomes¹.

HOW DOES BRUISE-EZE® WORK?

Fresh bruises appear blue to purplish in colour due to iron released from the breakdown of haemaglobin. Bruise-eze® contains the protein lactoferrin embedded in a liposome (patented Lipid Technology). Lactoferrin has a strong affinity for iron and so binds to (chelates) the released iron which is then broken down by our immune system. 

WHY IS LACTOFERRIN EMBEDDED IN A LIPOSOME?

Liposomes are structures that closely resemble cell membranes. They allow:

• Better penetration into the skin
• Provide stability and protect the lactoferrin from degradation
• Allow lactoferrin to be released in the right place

MORE ABOUT LACTOFERRIN

Lactoferrin is a natural protein which can be found in our innate immune system and as mentioned, is an iron chelator (binds to iron). This mode of action provides many beneficial properties which help to accelerate the healing process including:

• Iron binding – protects from the harmful effects of iron
• Anti-inflammatory – reduces swelling
• Re-Healing – promotes new cell formation
• Bacteriostatic – starves the bacteria of the iron it needs to replicate
• Antibiofilm – breaks down and stops the formation of mucilage that houses bacteria and other microorganisms
• Antioxidant – stops the formation of destructive free radicals and also binds to them

THE BRUISE-EZE® RANGE

3 Types Cream , Airless and Sterile 

• European Patent
• Manufactured in Italy
• ARTG included as medical devices
• may be used in conjunction with blood thinners
• no script needed
• 3 year shelf life
• Storage at <25˚C

BRUISE-EZE® CREAM 

• 30mL tube
  • original packaging
  • intended for use on intact skin

BRUISE-EZE® AIRLESS 

• 30mL airless pump dispenser
  • Easy to use
  • Metered dose
  • Aesthetically pleasing design
  • Avoids the danger of external contamination
  • intended to use on intact skin
  • May be used around mouth and eyes

WHAT ARE BRUISE-EZE® CREAM & AIRLESS INDICATED FOR?

• Bruises, Haematomas and Ecchymosis (different types of bruising)
• Remove the accumulation of iron and reduce inflammation associated with lymphoedema
• Dyschromia (discolouration) of bruises, haematomas, ecchymosis, post-operative ecchymosis
• Post sclerotherapy haemosiderinic dyschromia (Hyperpigmentation after varicose vein injections)
  • Can take up to 12 months to disappear without treatment
• CVI (Chronic Venous Insufficiency) dyschromia (Pooling of blood in the veins caused by poorly working veins and valves) and prevention of phlebostatic ulcers (Extreme result of CVI)
  • Current treatment includes the use of compression stockings to limit the pooling of blood. Bruise-eze® may be used in conjunction with compression treatment or on its own
• Phlebostatic ulcer dyschromia
• Post aesthetic laser treatments (non-ablative, epilation and vascular laser)
  • Has been observed to reduce patient ‘down time’ post treatment².

BRUISE-EZE® 2.B 

• ARTG Class IIB inclusion. It is the most specialized product in the portfolio.
• Only sterile product of its type on the market.
• 5 Sterile Single-use Applicators – 5mL
  • Main users will be healthcare professionals such as: Dermatologists, Cosmetic/Plastic Surgeons, Nurses (hospital, aged care facilities, home care), Phlebologists (Vein specialists)

WHAT IS BRUISE-EZE® 2.B INDICATED FOR?

• Post-Blepharoplasty (surgical removal of excess skin from eyelids and/or excess fat from below eyes.)
  • A very common side effect of this surgery is periorbital haematoma. Current treatment is to apply icebags. Bruise-eze® 2.B may be used on the face and one study showed that it reduced discoloration of haematoma by 31.5% versus 11% for Icebag treatment when applied 3 times per day for 1 week³.
• Post-surgical bruising
• Post-sclerotherapy haemosiderinic dyschromia
• Prevention of iron dependent venous ulcers
• Varicose ulcers (Also known as stasis, phlebostatic or venous ulcers)
• Delayed wound healing
• May be used on broken skin
• Pressure sores
• Fissures
• Burns
• Wound scarring
• Post aesthetic laser treatments (non-ablative, epilation and vascular laser)

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